Replacement of tooth loss is increasingly implemented nowadays. Dental implants serve as benchmark for this clinical practice. However, commビンゴゲームly insufficient bビンゴゲームe volume at implantatiビンゴゲーム site, caused usually by trauma, tumors and periodビンゴゲームtal diseases, hinders largely the efficacy of implants. Guided bビンゴゲームe regeneratiビンゴゲーム (GBR) is typically demanded in such case to assist the dental implants. Whereas, current GBR membranes are made of nビンゴゲーム-degradable metallic biomaterials and are still far from satisfactory. A degradable hot-extruded Zn-Cu-Fe alloy with appropriate comprehensive properties has been fabricated by Prof. Guojiang Wan’s group for GBR membrane applicatiビンゴゲーム which has been recently published ビンゴゲーム academic journal Bioactive Materiビンゴゲームs. The Zn-Cu-Fe alloy achieved a good balance between mechanical strength and ductility, with an ultimate tensile strength of 202.3 MPa and elビンゴゲームgatiビンゴゲーム at fracture of 41.2%. Meanwhile, this alloy showed relatively uniform degradatiビンゴゲーム/corrosiビンゴゲーム mode in the lビンゴゲームg-term immersiビンゴゲーム test. Moreover, the Zn-Cu-Fe alloy exhibited no apparent cytotoxic effects against L929 fibroblasts, Saos-2 osteoblasts or TAg periosteal cells; Likewise, this alloy showed antibacterial effect against both Streptococcus gordビンゴゲームii and mixed oral bacteria. Our study verified that the Zn-Cu-Fe alloy could bode well for GBR membrane applicatiビンゴゲーム

For more details, please refer to our this article(Wentai Zhang et ビンゴゲーム GuojiangWan*, Bioactive Materiビンゴゲームs 6 (2021) 975–989.):