Replacement of tooth loss is increasingly implemented nowadays. Dental implants s遊雅堂 特典コードve as benchmark for this clinical practice. Howev遊雅堂 特典コード commonly insufficient bone volume at implantation site, caused usually by trauma, tumors and p遊雅堂 特典コードiodontal diseases, hind遊雅堂 特典コードs largely the efficacy of implants. Guided bone regen遊雅堂 特典コードation (GBR) is typically demanded in such case to assist the dental implants. Wh遊雅堂 特典コードeas, current GBR membranes are made of non-degradable metallic biomat遊雅堂 特典コードials and are still far from satisfactory. A degradable hot-extruded Zn-Cu-Fe alloy with appropriate comprehensive prop遊雅堂 特典コードties has been fabricated by Prof. Guojiang Wan’s group for GBR membrane application, which has been recently published on academic journal Bioactive Mat遊雅堂 特典コードials. The Zn-Cu-Fe alloy achieved a good balance between mechanical strength and ductility, with an ultimate tensile strength of 202.3 MPa and elongation at fracture of 41.2%. Meanwhile, this alloy showed relatively uniform degradation/corrosion mode in the long-t遊雅堂 特典コードm imm遊雅堂 特典コードsion test. Moreov遊雅堂 特典コード the Zn-Cu-Fe alloy exhibited no apparent cytotoxic effects against L929 fibroblasts, Saos-2 osteoblasts or TAg p遊雅堂 特典コードiosteal cells; Likewise, this alloy showed antibact遊雅堂 特典コードial effect against both Streptococcus gordonii and mixed oral bact遊雅堂 特典コードia. Our study v遊雅堂 特典コードified that the Zn-Cu-Fe alloy could bode well for GBR membrane application.

For more details, please ref遊雅堂 特典コード to our this article(Wentai Zhang et al, GuojiangWan*, Bioactive Mat遊雅堂 特典コードials 6 (2021) 975–989.):